@prefix this: <https://w3id.org/np/RAfs0cOu754HVe7UQvH4DRREIJMAPpnMPtwCmDoCNKfgU> .
@prefix sub: <https://w3id.org/np/RAfs0cOu754HVe7UQvH4DRREIJMAPpnMPtwCmDoCNKfgU/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .

sub:Head {
  this: a np:Nanopublication;
    np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo .
}

sub:assertion {
  sub:clonaltracker-validation a obo:OBI_0000066, obo:OBI_0003693;
    dct:description "Development and validation of ClonalTracker, a tool that assesses for a pair of vancomycin-resistant Enterococcus faecium (VRE) genomes whether they are related through clonal spread or through horizontal transfer, by comparing the van operon, its carrying transposon, and whole-genome similarity. The method was validated on two previously analyzed public VRE datasets and applied to a third dataset of 323 vanB VRE isolates, in which clonal expansion was found to be the dominant dissemination mode. The tool is available at clonaltracker.nl.";
    dct:isPartOf <https://w3id.org/spaces/zonmw/antibiotica-resistentie-abr/541003005>;
    rdfs:label "ClonalTracker: development and validation of a method to elucidate dissemination patterns between VRE isolates";
    rdfs:seeAlso <https://doi.org/10.1101/2024.01.05.574403>, <https://www.clonaltracker.nl/>;
    prov:wasAssociatedWith orcid:0000-0001-9609-9401, orcid:0000-0003-1894-7545 .
}

sub:provenance {
  sub:assertion prov:wasDerivedFrom <https://doi.org/10.1101/2024.01.05.574403>, <https://projecten.zonmw.nl/nl/project/vre-crossword-horizontal-or-vertical-transmission-vancomycin-resistant-enterococcus-faecium> .
}

sub:pubinfo {
  obo:OBI_0000066 rdfs:label "study" .
  
  obo:OBI_0003693 rdfs:label "observational investigation" .
  
  orcid:0000-0001-9609-9401 foaf:name "Victoria Pascal Andreu" .
  
  orcid:0000-0002-1267-0234 foaf:name "Tobias Kuhn" .
  
  orcid:0000-0003-1894-7545 foaf:name "Anita C. Schürch" .
  
  this: dct:created "2026-08-14T06:00:00Z"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1267-0234;
    dct:license <https://creativecommons.org/publicdomain/zero/1.0/>;
    npx:hasNanopubType obo:OBI_0000066;
    npx:introduces sub:clonaltracker-validation;
    rdfs:label "Study: ClonalTracker: development and validation of a method to elucidate dissemination patterns between VRE isolates";
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RAcTpoh5Ra0ssqmcpOgWdaZ_YiPE6demO6cpw-2RvSNs8>;
    nt:wasCreatedFromPubinfoTemplate <https://w3id.org/np/RACJ58Gvyn91LqCKIO9zu1eijDQIeEff28iyDrJgjSJF8>,
      <https://w3id.org/np/RAoTD7udB2KtUuOuAe74tJi1t3VzK0DyWS7rYVAq1GRvw>, <https://w3id.org/np/RAukAcWHRDlkqxk7H2XNSegc1WnHI569INvNr-xdptDGI>;
    nt:wasCreatedFromTemplate <https://w3id.org/np/RAWaGj1HOf1_9D-zgvejQ3GCcCIFu4qBArSYKguPU0r5Y> .
  
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCwUtewGCpT5vIfXYE1bmf/Uqu1ojqnWdYxv+ySO80ul8Gu7m8KoyPAwuvaPj0lvPtHrg000qMmkxzKhYknEjq8v7EerxZNYp5B3/3+5ZpuWOYAs78UnQVjbHSmDdmryr4D4VvvNIiUmd0yxci47dTFUj4DvfHnGd6hVe5+goqdcwIDAQAB";
    npx:hasSignature "cj21hVqAT3XgKxyBlhaZ3wEJiJmF9XAF2TwITp4PTxA1IK0lH0sCI89tLmwr4i1I/BKk+Xi0jlckltu46zy61gfO4qrgoRP0L34sNgzes1roxpkeTPOs6skqgUQ0GxpCXMQLNPZgmCNEKj/NeiT2SCe7OULA8t3yLC1hP7TjbuY=";
    npx:hasSignatureTarget this:;
    npx:signedBy orcid:0000-0002-1267-0234 .
  
  <https://w3id.org/spaces/zonmw/antibiotica-resistentie-abr/541003005> nt:hasLabelFromApi
      "VRE-crossword, horizontal or vertical? Transmission of vancomycin-resistant Enterococcus faecium in Dutch hospitals" .
}